Exosome Evidence Index

Studies / Healing after procedures and wounds

Placental exosomes on the skin for healing after aesthetic procedures

Peredo M, Shivananjappa S, Journal of Drugs in Dermatology, 2024

Improvement reported, no control groupStrength of design, level 1 of 5: Single case or case series

Improvement reported, no control group: Patients improved, but without a comparison group there is no way to tell whether the treatment caused it.

Level 1 of 5: One patient or a handful, described without a comparison. It can raise an idea; it cannot show that a treatment works.

See the full key
Design
Case series
People
3 people
Made from
Placenta
How it was given
On the skin

What they found

The authors reported faster recovery, with less redness, swelling, and pain, in all three cases.

What limits it

Three patients, no comparison group, and follow-up measured in days. Product used: Exovex.

Read the study

Other studies of healing after procedures and wounds

  1. No benefit over controlStrength of design, level 3 of 5: Controlled trial

    Donor platelet vesicles injected into small skin wounds

    Johnson J et al., Journal of Extracellular Vesicles, 2023. 11 healthy volunteers. Made from: donor platelets.

    Safe and well tolerated. Wounds healed in about 23 days on average whether they got the vesicles or placebo.

  2. Better than controlStrength of design, level 3 of 5: Controlled trial

    The patient's own serum vesicles for chronic venous leg ulcers

    Gibello L et al., Pharmacological Research, 2023. About 5 patients. Made from: patient's own blood serum.

    Treated ulcers formed more healthy granulation tissue than sham-treated ulcers: 3 of 5 treated ulcers reached 75–100% granulation, compared with none of the sham-treated ones.