Exosome Evidence Index

Studies / Chronic kidney disease

Umbilical cord stem cell vesicles for stage 3–4 chronic kidney disease

Nassar W et al., Biomaterials Research, 2016

Better than controlStrength of design, level 3 of 5: Controlled trial

Better than control: The treated group did better than the comparison group on the main measures.

Level 3 of 5: Treated patients were compared with a control: placebo, another treatment, or the untreated side of the face. Most exosome trials at this level are small and short.

See the full key
Design
Randomized, placebo-controlled (phase II/III)
People
40 people
Made from
Umbilical cord
How it was given
Two doses

What they found

The authors reported better kidney function (eGFR) and lower inflammation markers in the treated group than with placebo.

What limits it

A small, single-center trial.

Read the study