Placental stem cell exosomes injected after keloid removal
Chernoff G, Journal of Surgery, 2022
Improvement reported, no control group
Improvement reported, no control group: Patients improved, but without a comparison group there is no way to tell whether the treatment caused it.
Level 2 of 5: A group was treated and followed, but nobody was left untreated for comparison. Improvement may come from time, other care, or the placebo effect.
See the full key- Design
- Single-group pilot, no control
- People
- 21 people
- Made from
- Placenta
- How it was given
- Injected into the wound after the keloid was cut out
What they found
18 of 21 patients had no keloid regrowth over 2 years.
What limits it
Without a comparison group, the share of the result owed to exosomes rather than surgery is unknown. Some patients with darker skin developed dark spots after inflammation. Product used: XoGlo (Kimera Labs).